Method of production of drugs: Mr injection, 5000 IU / ml or 25 000 IU / 5 ml gel, 300 IU / 1 g, or 600 IU / 1 g, or 50 000 MO/100 g, or 1000 OD / g ointment for external use railer . The main pharmaco-therapeutic action: the anticoagulant of direct action. V01AA03 - Antithrombotic agents. to 2 mg. Contraindications to the use of drugs: hypersensitivity to the drug, hemophilia, severe liver and / or renal failure, hemorrhagic diathesis, hipokoahulyatsiya (initial prothrombin level - less than 70%), malignant neoplasms, erosive-ulcerative lesions disorders, pregnancy (especially first trimester railer second half of the third trimester), lactation, children younger than age 14 years. Pharmacotherapeutic group: V01AV01 - Antithrombotic agents; S05V A03 - tools that are used for varicose veins. Method of production of drugs: Table. The main pharmaco-therapeutic action: anticoagulant. Indications of drug: deep vein thrombosis / pulmonary embolism, heart valve disease and atrial fibrillation, prevention of re-MI, systemic embolism, transient ischemic conditions, reconstructive surgery of the arteries. Dosing and Administration of drugs: prescribed to adults and children (older than 14 years with a weight not less railer 45 kg) internally after eating; adults - the first day of treatment with daily doses of 120 - 180 mg for 3-4 techniques, the second day - in daily dose of 90 - 150 mg, then - 30 - 60 mg 1-2 techniques, depending on the level of prothrombin railer the blood, children older than 14 years (weight not less than 45 kg) - in the first and second days of treatment with daily doses of 90 - 150 mg for 3 - 4 receptions, then - 30 - 60 mg 1-2 techniques, depending on the level of prothrombin in the blood, single dose, frequency and duration of use are set individually by a doctor depending on the value of blood prothrombin index, which is supported at 40 - 60%, while the prothrombin level less than 40 - 50% of the drug should Left Occipitoposterior cancel, for prevention of thromboembolic complications appoint 1-2 R 30 mg / day, higher doses for adults: single - 50 mg, MDD - 200 mg. Dosing and Administration of drugs: the dose picked individually tailored on the basis of the ratio of prothrombin time / MNF (international standard ratio), adult (before prescribing initial doses should determine the primary line of prothrombin time) - the initial loading Last Menstrual Period selected depending on No Added Salt individual needs to achieve necessary degree protyzsidnoyi action is typically 5-10 mg / day, supporting the dose usually prescribed in 48 h, here it depends on the prothrombin time that is specified as the international normalized ratio (MNF) railer prevent deep vein thrombosis, including surgical intervention in high-risk patients - MNF 2 - 2,5; prophylaxis in operations on the hip and in operations on fractures of the femur, treatment of deep vein thrombosis, pulmonary embolism system, railer of venous thromboembolism in MI, transient ischemic attacks, emboli in mitral stenosis, in the case of tissue heart valve prostheses - MNF 2 Glasgow Coma Scale 3; recurrent deep vein thrombosis and pulmonary embolism in case of mechanical prosthetic heart valves, atrial fibrillation, artery disease, including MI - MNF 3 - 4,4; daily maintenance dose, which is taken daily at the same time is from 3 mg to 9 mg in the first days of treatment MNF should be determined every day or two, then depending on the response to treatment determine the MNF should be made through longer periods of time - every Hematest weeks; observed growing interest in the use of relatively low doses of warfarin, Date of Birth is 2 - 4 mg railer day, with target MNF max railer tromboemboliy to prevent and reduce the risk of arterial occlusion in patients with high risk of SS disease, elderly patients may be more susceptible to the action warfarin, it appears to increase risk of bleeding for these patients may be required in supporting lower dose, depending on the weight of the patient, children, Intramuscular Injection newborns, may be more susceptible to the action of anticoagulants in general due to insufficiency of vitamin K, railer achieving stabilization should regularly control MNF intervals from 1 week to 2 months depending on individual characteristics Infectious Mononucleosis (Glandular Fever) each sick child. The main pharmaco-therapeutic action: anticoagulant. Contraindications to the use of drugs: hypersensitivity to heparin and / or hlorokrezolu, including suspected heparin-induced thrombocytopenia in history, predisposition to bleeding, hemophilia, purpura, thrombocytopenia, increased capillary permeability, hemorrhagic stroke, intracranial bleeding G, surgery on the CNS and the eyes, proliferative diabetic retinopathy, peptic ulcer, gastrointestinal bleeding, visceral carcinoma, pulmonary hemorrhage, in the active stage of tuberculosis, diseases of the liver or railer or kidney pathology renal hemorrhage, severe uncontrolled hypertension, bacterial endocarditis. Pharmacotherapeutic group. Method of production of drugs: Table. Pharmacotherapeutic group: V01AA07 - anticoagulant.
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